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Next Generation Sequencing: Revolutionizing Genomics
Next Generation Sequencing (NGS) has emerged as one of the most transformative technologies in modern biology and medicine. By enabling rapid and accurate analysis of entire genomes, NGS has opened new frontiers in genomics, personalized medicine, and disease research. Its ability to generate massive amounts of genetic data quickly and cost-effectively has made it indispensable for both research and clinical applications.
Understanding Next Generation Sequencing
Next Generation Sequencing refers to high-throughput DNA sequencing technologies that allow scientists to determine the precise order of nucleotides in a DNA or RNA sample. Unlike traditional Sanger sequencing, which processes one DNA fragment at a time, NGS can sequence millions of fragments simultaneously. This parallelization dramatically reduces time and cost, making large-scale genomic studies feasible.
NGS works through several key steps: sample preparation, library construction, sequencing, and data analysis. DNA or RNA is first fragmented, and adapters are added…